Knee pathologies including focal cartilage injuries, osteoarthritis and ligament injuries are common. The use of biologic agents has emerged as an option for treating these diseases. Platelet-rich plasma (PRP) has gained significant interest for treating common sports medicine injuries....read more
This study talks about newer biologic treatments in use to potentially slow disease progression in patients with knee osteoarthritis. These include hyaluronic acid, platelet-rich plasma (PRP), bone-marrow aspirate concentrate (BMAC) and adipose-derived mesenchymal stem cells. Believed to affect tissue...read more
This study discusses the effects of mesenchymal stem cells (MSCs) on cartilage regeneration and patient-reported pain and function. Osteoarthritis (OA) is one of the most common causes of joint pain and disability; MSCs have been extensively studied as an...read more
This study reviews the current evidence surrounding rotator cuff repairs (RCR). Rotator cuff tears are a frequent cause of shoulder pain and disability; despite resolution of pain and outcome measures following surgery, incomplete healing or re-tearing following surgery is...read more
Hip preservation treatments have become increasingly investigated in the past few decades. Particularly with the advent of orthobiologics, such as platelet-rich plasma (PRP) and stem cells, common intra-articular hip pathologies are now managed with injections. However, as studies have...read more
This study talks about the role of biologics in common ligament injuries. There is a significant potential with the use of biologics given it may enhance tissue healing. Biologics may provide an alternative to surgical intervention when nonoperative treatment...read more
This study evaluates the current literature on the safety and efficacy of intra-articular cellular therapy injections. For patients with osteoarthritis or focal cartilage defects, intra-articular cellular therapy is appealing in that it may help with cartilage regeneration. The current...read more
This study talks about outcomes following the use of bone marrow aspirate concentrate (BMAC) in patients with knee osteoarthritis and cartilage defects. BMAC has emerged as an important biological tool for the orthopaedic surgeon because it is one of...read more
This article reviews biological treatment options for articular cartilage repair, including platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC) and cell-based therapies. Articular cartilage damage is seen most commonly in focal chondral lesions and early osteoarthritis and is a...read more
This article reviews the current literature surrounding the use of human adipose-derived mesenchymal stem cells (ADSCs) in the management of various orthopedic diseases. ADSCs have gained attention due to their potential for expediting healing and the ease of delivery...read more
