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Orthopedic Blog - Biologic Publications
Biologic Publications

Biological treatment of the knee with platelet-rich plasma or bone marrow aspirate concentrates

Knee pathologies including focal cartilage injuries, osteoarthritis and ligament injuries are common. The use of biologic agents has emerged as an option for treating these diseases. Platelet-rich plasma (PRP) has gained significant interest for treating common sports medicine injuries....read more


Biologic Publications

The Role of Orthobiologics in the Management of Osteoarthritis and Focal Cartilage Defects

This study talks about newer biologic treatments in use to potentially slow disease progression in patients with knee osteoarthritis. These include hyaluronic acid, platelet-rich plasma (PRP), bone-marrow aspirate concentrate (BMAC) and adipose-derived mesenchymal stem cells. Believed to affect tissue...read more


Biologic Publications

Regenerative Potential of Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis and Chondral Defects: A Systematic Review and Meta-Analysis

This study discusses the effects of mesenchymal stem cells (MSCs) on cartilage regeneration and patient-reported pain and function. Osteoarthritis (OA) is one of the most common causes of joint pain and disability; MSCs have been extensively studied as an...read more


Biologic Publications

Rationale for Biologic Augmentation of Rotator Cuff Repairs

This study reviews the current evidence surrounding rotator cuff repairs (RCR). Rotator cuff tears are a frequent cause of shoulder pain and disability; despite resolution of pain and outcome measures following surgery, incomplete healing or re-tearing following surgery is...read more


Biologic Publications

Preparation Methods and Clinical Outcomes of Platelet-Rich Plasma for Intra-articular Hip Disorders

Hip preservation treatments have become increasingly investigated in the past few decades. Particularly with the advent of orthobiologics, such as platelet-rich plasma (PRP) and stem cells, common intra-articular hip pathologies are now managed with injections. However, as studies have...read more


Biologic Publications

Ortho-Biologics for Ligament Repair and Reconstruction

This study talks about the role of biologics in common ligament injuries. There is a significant potential with the use of biologics given it may enhance tissue healing. Biologics may provide an alternative to surgical intervention when nonoperative treatment...read more


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